Experimental Study Article Example | Topics and Well Written Essays - 500 words

Experimental Study - Article ExampleThe other(a) exposures of interest include apply of nitrous oxide, the utilization of slightly hypoxic mixtures during anesthesia, and postoperative opioid administration.The effectiveness of dexamethasone as antiemetic was compared with the two serotonin subtype 3 antagonists ondansetron and granisetron in 80 patients divided into four groups undergoing laparoscopic cholecystectomy.Group 1, consisting of retain patients, received 0.9% NaCl group 2 patients received ondansetron 4 mg i.v. group 3 patients received granisetron 3 mg i.v. and group 4 patients received dexamethasone 8 mg i.v., all before the evocation of anesthesia. Both nausea and vomiting were assessed during the first 24 h after the procedure.Inclusion Criteria A total of 80 American nightclub of Anesthesiologists (ASA) physical class III patients scheduled for laparoscopic cholecystectomy were included. The age ramble was from 21 to 75 years (mean 51.5 years). Each patient gav e his or her written consent to participate in the study. The study was approved by the Medical University ethics committee.The exclusion criteria The patients exclusion criteria were as follows American Society of Anesthesiology (ASA) physical class IIIIV age over 75 years body mickle index above 30 pregnancy smoking signs of gastrointestinal, endocrine, renal, hepatic or immunological disease use of opioids or tranquillizers less than 1 week before the operation treatment with steroids history of alcohol or drug abuse history of motion sickness preoperative diagnosis of gallbladder empyema and previous endoscopic sphincterotomy for common bile duct stones and conversion to open cholecystectomy.The incidence of nausea and vomiting was recorded during triplet assessment periods, 06 h, 612 h, and 1224 h, by nursing cater without knowledge of which antiemetic the patients had received. Both nausea and vomiting were